4F37

Structure of the tethered N-terminus of Alzheimer's disease A peptide

Summary for 4F37

• Entry DOI: 10.2210/pdb4f37/pdb
• Related: 1AYI 3BKJ
• Descriptor: Colicin-E7 immunity protein, Im7 immunity protein, Fab WO2 anti-amyloid-beta antibody Fab fragment, ... (4 entities in total)
• Functional Keywords: amyloid-beta, alzheimer's disease, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 6
• Total formula weight: 126379.85

Authors

Nisbet, R.M.,Nuttall, S.D.,Caine, J.M.,Rober, R.,Hittaki, M.,Pearce, L.A.,Davydova, N.,Masters, C.L.,Varghese, J.N.,Streltsov, V.A. (deposition date: 2012-05-09, release date: 2013-05-15, Last modification date: 2014-09-03)

• Primary citation: Nisbet, R.M.,Nuttall, S.D.,Robert, R.,Caine, J.M.,Dolezal, O.,Hattarki, M.,Pearce, L.A.,Davydova, N.,Masters, C.L.,Varghese, J.N.,Streltsov, V.A.; Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-beta peptide.; Proteins, 81:1748-1758, 2013; PubMed: 23609990; DOI: 10.1002/prot.24312

Experimental method

X-RAY DIFFRACTION (2.57 Å)