4F2Y

Structure of 3'-Fluoro Cyclohexenyl Nucleic Acid Decamer

Summary for 4F2Y

• Entry DOI: 10.2210/pdb4f2y/pdb
• Related: 4F2X
• Descriptor: 5'-D(*GP*CP*GP*TP*AP*(XTF)P*AP*CP*GP*C)-3', MAGNESIUM ION (3 entities in total)
• Functional Keywords: fluoro cyclohexenyl nucleic acid, f-cena, modified dna, a-form dna, dna
• Total number of polymer chains: 2
• Total formula weight: 6194.68

Authors

Pallan, P.S.,Egli, M. (deposition date: 2012-05-08, release date: 2012-05-30, Last modification date: 2023-09-13)

• Primary citation: Seth, P.P.,Yu, J.,Jazayeri, A.,Pallan, P.S.,Allerson, C.R.,Ostergaard, M.E.,Liu, F.,Herdewijn, P.,Egli, M.,Swayze, E.E.; Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2'-Fluoro RNA.; J.Org.Chem., 77:5074-5085, 2012; PubMed: 22591005; DOI: 10.1021/jo300594b

Experimental method

X-RAY DIFFRACTION (1.59 Å)