4EY0
Structure of tandem SH2 domains from PLCgamma1
Summary for 4EY0
| Entry DOI | 10.2210/pdb4ey0/pdb |
| Descriptor | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (2 entities in total) |
| Functional Keywords | sh2 domain, plcgamma specific array, interaction domain, fibroblast growth factor receptor 1, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell projection, lamellipodium: P19174 |
| Total number of polymer chains | 4 |
| Total formula weight | 114504.58 |
| Authors | Cole, A.R.,Mas-Droux, C.P.,Bunney, T.D.,Katan, M. (deposition date: 2012-05-01, release date: 2012-10-31, Last modification date: 2013-06-19) |
| Primary citation | Bunney, T.D.,Esposito, D.,Mas-Droux, C.,Lamber, E.,Baxendale, R.W.,Martins, M.,Cole, A.,Svergun, D.,Driscoll, P.C.,Katan, M. Structural and Functional Integration of the PLCgamma Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation. Structure, 20:2062-2075, 2012 Cited by PubMed: 23063561DOI: 10.1016/j.str.2012.09.005 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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