4EY0
Structure of tandem SH2 domains from PLCgamma1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | polymer | 246 | 28626.1 | 4 | UniProt (P19174) Pfam (PF00017) In PDB | Homo sapiens (human) | PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, PLC-II, Phospholipase C-gamma-1, PLC-gamma-1 |
2 | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 545 - 790 (UniProt: P19174)
PDB | External Database | Details |
---|---|---|
Phe 771 | Tyr 771 | ENGINEERED MUTATION |
Phe 775 | Tyr 775 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 114504.6 | |
All* | Total formula weight | 114504.6 |