4EY0
Structure of tandem SH2 domains from PLCgamma1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | polymer | 246 | 28626.1 | 4 | UniProt (P19174) Pfam (PF00017) | Homo sapiens (human) | PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, PLC-II, Phospholipase C-gamma-1, PLC-gamma-1 |
| 2 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 545 - 790 (UniProt: P19174)
| PDB | External Database | Details |
|---|---|---|
| Phe 771 | Tyr 771 | engineered mutation |
| Phe 775 | Tyr 775 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 114504.6 | |
| All* | Total formula weight | 114504.6 |
