4EXP

Structure of mouse Interleukin-34 in complex with mouse FMS

Summary for 4EXP

• Entry DOI: 10.2210/pdb4exp/pdb
• Related: 4EXN
• Descriptor: Interleukin-34, Macrophage colony-stimulating factor 1 receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: extended 4-helix bundle, immunoglobunin, beta-sandwich, cytokine-transferase complex, cytokine/transferase
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 2
• Total formula weight: 52656.10

Authors

Liu, H.,Leo, C.,Chen, X.,Wong, B.R.,Williams, L.T.,Lin, H.,He, X. (deposition date: 2012-04-30, release date: 2012-05-30, Last modification date: 2023-09-13)

• Primary citation: Liu, H.,Leo, C.,Chen, X.,Wong, B.R.,Williams, L.T.,Lin, H.,He, X.; The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.; Biochim.Biophys.Acta, 1824:938-945, 2012; PubMed: 22579672; DOI: 10.1016/j.bbapap.2012.04.012

Experimental method

X-RAY DIFFRACTION (2.8 Å)