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4EXP

Structure of mouse Interleukin-34 in complex with mouse FMS

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Interleukin-34polymer17720547.91UniProt (Q8R1R4)
Pfam (PF15036)
Mus musculus (mouse)IL-34
2B
(X)
Macrophage colony-stimulating factor 1 receptorpolymer28331223.31UniProt (P09581)
Pfam (PF00047)
Mus musculus (mouse)FMS, CSF-1 receptor, CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms
3C, D, E, F
(A, X)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
4G, H
(A, X)
waterwater18.0198Chemie (HOH)
Sequence modifications
A: 21 - 194 (UniProt: Q8R1R4)
PDBExternal DatabaseDetails
Ala 195-expression tag
Ala 196-expression tag
Ala 197-expression tag
X: 20 - 298 (UniProt: P09581)
PDBExternal DatabaseDetails
Ala 17-expression tag
Asp 18-expression tag
Pro 19-expression tag
His 299-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight51771.3
Non-Polymers*Number of molecules4
Total formula weight884.8
All*Total formula weight52656.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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