4EXM

The crystal structure of an engineered phage lysin containing the binding domain of pesticin and the killing domain of T4-lysozyme

Summary for 4EXM

Entry DOI	10.2210/pdb4exm/pdb
Related	4EPI
Descriptor	Pesticin, Lysozyme Chimera (2 entities in total)
Functional Keywords	bacterial lysin, toxin, hydrolase
Biological source	Yersinia pestis More
Cellular location	Host cytoplasm : P00720
Total number of polymer chains	4
Total formula weight	158800.02
Authors	Seddiki, N.,Noinaj, N.,Fairman, J.W.,Lukacik, P.,Barnard, T.J.,Buchanan, S.K. (deposition date: 2012-04-30, release date: 2012-06-20, Last modification date: 2023-09-13)
Primary citation	Lukacik, P.,Barnard, T.J.,Keller, P.W.,Chaturvedi, K.S.,Seddiki, N.,Fairman, J.W.,Noinaj, N.,Kirby, T.L.,Henderson, J.P.,Steven, A.C.,Hinnebusch, B.J.,Buchanan, S.K. Structural engineering of a phage lysin that targets Gram-negative pathogens. Proc.Natl.Acad.Sci.USA, 109:9857-9862, 2012 Cited by PubMed: 22679291 DOI: 10.1073/pnas.1203472109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation