4EXM
The crystal structure of an engineered phage lysin containing the binding domain of pesticin and the killing domain of T4-lysozyme
Summary for 4EXM
Entry DOI | 10.2210/pdb4exm/pdb |
Related | 4EPI |
Descriptor | Pesticin, Lysozyme Chimera (2 entities in total) |
Functional Keywords | bacterial lysin, toxin, hydrolase |
Biological source | Yersinia pestis More |
Cellular location | Host cytoplasm : P00720 |
Total number of polymer chains | 4 |
Total formula weight | 158800.02 |
Authors | Seddiki, N.,Noinaj, N.,Fairman, J.W.,Lukacik, P.,Barnard, T.J.,Buchanan, S.K. (deposition date: 2012-04-30, release date: 2012-06-20, Last modification date: 2023-09-13) |
Primary citation | Lukacik, P.,Barnard, T.J.,Keller, P.W.,Chaturvedi, K.S.,Seddiki, N.,Fairman, J.W.,Noinaj, N.,Kirby, T.L.,Henderson, J.P.,Steven, A.C.,Hinnebusch, B.J.,Buchanan, S.K. Structural engineering of a phage lysin that targets Gram-negative pathogens. Proc.Natl.Acad.Sci.USA, 109:9857-9862, 2012 Cited by PubMed: 22679291DOI: 10.1073/pnas.1203472109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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