4EWS

Crystal structure of cholesteryl ester transfer protein in complex with inhibitors

4EWS の概要

• エントリーDOI: 10.2210/pdb4ews/pdb
• 関連するPDBエントリー: 2OBD
• 分子名称: CETP, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTERYL OLEATE, ... (8 entities in total)
• 機能のキーワード: cholestryl ester transfer protein, high-density lipoprotein, low-density lipoprotein, cholestryl ester transfer protein-inhibitor complex, lipid transport-inhibitor complex, lipid transport/inhibitor
• 由来する生物種: Homo sapiens
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56850.99

構造登録者

Liu, S.,Qiu, X. (登録日: 2012-04-27, 公開日: 2012-09-05, 最終更新日: 2023-09-13)

• 主引用文献: Liu, S.,Mistry, A.,Reynolds, J.M.,Lloyd, D.B.,Griffor, M.C.,Perry, D.A.,Ruggeri, R.B.,Clark, R.W.,Qiu, X.; Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.; J.Biol.Chem., 287:37321-37329, 2012; PubMed: 22961980; DOI: 10.1074/jbc.M112.380063

実験手法

X-RAY DIFFRACTION (2.59 Å)