4EWD
Study on structure and function relationships in human Pirin with Mn ion
Summary for 4EWD
Entry DOI | 10.2210/pdb4ewd/pdb |
Related | 4ERO 4EWA 4EWB 4EWE |
Descriptor | Pirin, MANGANESE (II) ION (3 entities in total) |
Functional Keywords | beta sandwich, cupin, metal binding protein, transcription cofactor activity, protein binding, nucleus, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O00625 |
Total number of polymer chains | 1 |
Total formula weight | 32214.33 |
Authors | Liu, F.,Rehmani, I.,Chen, L.,Fu, R.,Serrano, V.,Wilson, D.W.,Liu, A. (deposition date: 2012-04-26, release date: 2013-05-29, Last modification date: 2024-02-28) |
Primary citation | Liu, F.,Rehmani, I.,Esaki, S.,Fu, R.,Chen, L.,de Serrano, V.,Liu, A. Pirin is an iron-dependent redox regulator of NF-kappa B. Proc.Natl.Acad.Sci.USA, 110:9722-9727, 2013 Cited by PubMed: 23716661DOI: 10.1073/pnas.1221743110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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