4ETQ

Vaccinia virus D8L IMV envelope protein in complex with Fab of murine IgG2a LA5

Summary for 4ETQ

• Entry DOI: 10.2210/pdb4etq/pdb
• Related: 4E9O 4EBQ
• Descriptor: anti-vaccinia D8L antigen murine monoclonal IgG2a antibody LA5, heavy chain, anti-vaccinia D8L antigen murine monoclonal IgG2a antibody LA5, light chain, IMV membrane protein, ... (8 entities in total)
• Functional Keywords: variable domain, constant domain, igg2a, igg domain, cdr, hypervariable region, neutralizing antibody, beta sheet, carbonic anhydrase fold, loose knot, chondroitin-sulfate binding site, delta 262, immune system-viral protein complex, immune system/viral protein
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 157827.42

Authors

Matho, M.H.,Zajonc, D.M. (deposition date: 2012-04-24, release date: 2012-06-06, Last modification date: 2023-09-13)

• Primary citation: Matho, M.H.,Maybeno, M.,Benhnia, M.R.,Becker, D.,Meng, X.,Xiang, Y.,Crotty, S.,Peters, B.,Zajonc, D.M.; Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5.; J.Virol., 86:8050-8058, 2012; PubMed: 22623786; DOI: 10.1128/JVI.00836-12

Experimental method

X-RAY DIFFRACTION (2.1 Å)