Crystal structure of the extracellular domain of PknH from Mycobacterium tuberculosis

Summary for 4ESQ

DescriptorSerine/threonine protein kinase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TERBIUM(III) ION, ... (4 entities in total)
Functional Keywordsreceptor kinase, membrane, transferase
Biological sourceMycobacterium tuberculosis
Total number of polymer chains1
Total molecular weight21189.08
Cavazos, A.,Prigozhin, D.M.,Alber, T. (deposition date: 2012-04-23, release date: 2012-07-18, Last modification date: 2017-11-15)
Primary citation
Cavazos, A.,Prigozhin, D.M.,Alber, T.
Structure of the sensor domain of Mycobacterium tuberculosis PknH receptor kinase reveals a conserved binding cleft.
J.Mol.Biol., 422:488-494, 2012
PubMed: 22727744 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2012.06.011
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.196200.6%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-16