4EOT

Crystal structure of the MafA homodimer bound to the consensus MARE

Summary for 4EOT

• Entry DOI: 10.2210/pdb4eot/pdb
• Descriptor: Transcription factor MafA, 5'-D(*CP*CP*GP*GP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*GP*G)-3', 5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*GP*CP*AP*CP*CP*G)-3', ... (5 entities in total)
• Functional Keywords: leucine zipper, transcription factor, dna binding, nucleus, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q8NHW3
• Total number of polymer chains: 4
• Total formula weight: 34808.16

Authors

Lu, X.,Guanga, G.,Wan, C.,Rose, R.B. (deposition date: 2012-04-15, release date: 2012-11-28, Last modification date: 2023-09-13)

• Primary citation: Lu, X.,Guanga, G.P.,Wan, C.,Rose, R.B.; A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities.; Biochemistry, 51:9706-9717, 2012; PubMed: 23148532; DOI: 10.1021/bi301248j

Experimental method

X-RAY DIFFRACTION (2.855 Å)