4EOT
Crystal structure of the MafA homodimer bound to the consensus MARE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transcription factor MafA | polymer | 95 | 11453.2 | 2 | UniProt (Q8NHW3) Pfam (PF03131) | Homo sapiens (human) | Pancreatic beta-cell-specific transcriptional activator, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A |
| 2 | C (C) | 5'-D(*CP*CP*GP*GP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*GP*G)-3' | polymer | 19 | 5886.8 | 1 | |||
| 3 | D (D) | 5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*GP*CP*AP*CP*CP*G)-3' | polymer | 19 | 5726.7 | 1 | |||
| 4 | E, F, G (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A, B: 226 - 318 (UniProt: Q8NHW3)
| PDB | External Database | Details |
|---|---|---|
| Gly 224 | - | expression tag |
| Ser 225 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 34520.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 288.2 | |
| All* | Total formula weight | 34808.2 |
