4EOM
Thr 160 phosphorylated CDK2 H84S, Q85M, Q131E - human cyclin A3 complex with ATP
Summary for 4EOM
Entry DOI | 10.2210/pdb4eom/pdb |
Related | 4EOI 4EOJ 4EOK 4EOL 4EON 4EOO 4EOP 4EOQ 4EOR 4EOS |
Descriptor | Cyclin-dependent kinase 2, Cyclin-A2, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | protein kinase, cell cycle, complex, phosphorylation, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton, centrosome: P24941 Nucleus: P20248 |
Total number of polymer chains | 4 |
Total formula weight | 128837.27 |
Authors | Echalier, A.,Cot, E.,Camasses, A.,Hodimont, E.,Hoh, F.,Sheinerman, F.,Krasinska, L.,Fisher, D. (deposition date: 2012-04-14, release date: 2013-02-06) |
Primary citation | Echalier, A.,Cot, E.,Camasses, A.,Hodimont, E.,Hoh, F.,Jay, P.,Sheinerman, F.,Krasinska, L.,Fisher, D. An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity. Chem.Biol., 19:1028-1040, 2012 Cited by PubMed: 22921070DOI: 10.1016/j.chembiol.2012.06.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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