4EOM
Thr 160 phosphorylated CDK2 H84S, Q85M, Q131E - human cyclin A3 complex with ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Cyclin-dependent kinase 2 | polymer | 301 | 34250.7 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | Cell division protein kinase 2, p33 protein kinase |
| 2 | B, D | Cyclin-A2 | polymer | 258 | 29624.3 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | Homo sapiens (human) | Cyclin-A |
| 3 | A, C | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 4 | A, C, D | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 297 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Pro -3 | - | EXPRESSION TAG |
| Leu -2 | - | EXPRESSION TAG |
| Gly -1 | - | EXPRESSION TAG |
| Ser 0 | - | EXPRESSION TAG |
| Ser 84 | His 84 | ENGINEERED MUTATION |
| Met 85 | Gln 85 | ENGINEERED MUTATION |
| Glu 131 | Gln 131 | ENGINEERED MUTATION |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127750.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1087.3 | |
| All* | Total formula weight | 128837.3 |
