4EN9

Crystal structure of HA70 (HA3) subcomponent of Clostridium botulinum type C progenitor toxin in complex with alpha 2-6-sialyllactosamine

Summary for 4EN9

Entry DOI	10.2210/pdb4en9/pdb
Related	2ZOE 2ZS6 4EN6 4EN7 4EN8
Related PRD ID	PRD_900046
Descriptor	Hemagglutinin components HA-22/23/53, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, (4R)-2-METHYLPENTANE-2,4-DIOL, ... (5 entities in total)
Functional Keywords	carbohydrate/sugar binding, sugar binding protein
Biological source	Clostridium botulinum More
Total number of polymer chains	2
Total formula weight	74649.87
Authors	Yamashita, S.,Yoshida, H.,Tonozuka, T.,Nishikawa, A.,Kamitori, S. (deposition date: 2012-04-12, release date: 2012-06-06, Last modification date: 2023-11-08)
Primary citation	Yamashita, S.,Yoshida, H.,Uchiyama, N.,Nakakita, Y.,Nakakita, S.,Tonozuka, T.,Oguma, K.,Nishikawa, A.,Kamitori, S. Carbohydrate recognition mechanism of HA70 from Clostridium botulinum deduced from X-ray structures in complexes with sialylated oligosaccharides Febs Lett., 586:2404-2410, 2012 Cited by PubMed: 22684008 DOI: 10.1016/j.febslet.2012.05.055 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.64 Å)

Structure validation