4EK6
Crystal structure of the cdk2 in complex with aminopyrazole inhibitor
Summary for 4EK6
Entry DOI | 10.2210/pdb4ek6/pdb |
Related | 4EK3 4EK4 4EK5 |
Descriptor | Cyclin-dependent kinase 2, N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-[4-(thiophen-2-yl)phenyl]acetamide (3 entities in total) |
Functional Keywords | alpha and beta protein (a+b), transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: P24941 |
Total number of polymer chains | 1 |
Total formula weight | 34325.94 |
Authors | Kang, Y.N.,Stuckey, J.A. (deposition date: 2012-04-09, release date: 2013-05-01, Last modification date: 2017-11-15) |
Primary citation | Kang, Y.N.,Stuckey, J.A. Crystal structure of the cdk2 in complex with aminopyrazole inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (1.52 Å) |
Structure validation
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