4EIH

Crystal structure of Arg SH2 domain

Summary for 4EIH

Entry DOI	10.2210/pdb4eih/pdb
Descriptor	Abelson tyrosine-protein kinase 2, CHLORIDE ION (3 entities in total)
Functional Keywords	sh2 domain, protein/protein interaction, phosphotyrosine, phosphopeptide, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton: P42684
Total number of polymer chains	1
Total formula weight	12798.75
Authors	Liu, W.,MacGrath, S.M.,Koleske, A.J.,Boggon, T.J. (deposition date: 2012-04-05, release date: 2013-04-10, Last modification date: 2023-09-13)
Primary citation	Gifford, S.M.,Liu, W.,Mader, C.C.,Halo, T.L.,Machida, K.,Boggon, T.J.,Koleske, A.J. Two Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated Cortactin. J.Biol.Chem., 289:19704-19713, 2014 Cited by PubMed: 24891505 DOI: 10.1074/jbc.M114.556480 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation