4EHY
Crystal structure of LpxK from Aquifex aeolicus in complex with ADP/Mg2+ at 2.2 angstrom resolution
Summary for 4EHY
Entry DOI | 10.2210/pdb4ehy/pdb |
Related | 4EHW 4EHX |
Descriptor | Tetraacyldisaccharide 4'-kinase, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | membrane protein, kinase, lipid a, p-loop, p-loop containing nucleoside triphosphate hydrolase, disaccharide-1-phosphate 4'-kinase, membrane, transferase, lipid metabolism, tetraacyldisaccharide 4'-kinase |
Biological source | Aquifex aeolicus |
Total number of polymer chains | 1 |
Total formula weight | 37360.97 |
Authors | Emptage, R.P.,Daughtry, K.D.,Pemble IV, C.W.,Raetz, C.R.H. (deposition date: 2012-04-04, release date: 2012-08-29, Last modification date: 2023-09-13) |
Primary citation | Emptage, R.P.,Daughtry, K.D.,Pemble, C.W.,Raetz, C.R. Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface. Proc.Natl.Acad.Sci.USA, 109:12956-12961, 2012 Cited by PubMed: 22826246DOI: 10.1073/pnas.1206072109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.199 Å) |
Structure validation
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