4EHY

Crystal structure of LpxK from Aquifex aeolicus in complex with ADP/Mg2+ at 2.2 angstrom resolution

4EHY の概要

• エントリーDOI: 10.2210/pdb4ehy/pdb
• 関連するPDBエントリー: 4EHW 4EHX
• 分子名称: Tetraacyldisaccharide 4'-kinase, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: membrane protein, kinase, lipid a, p-loop, p-loop containing nucleoside triphosphate hydrolase, disaccharide-1-phosphate 4'-kinase, membrane, transferase, lipid metabolism, tetraacyldisaccharide 4'-kinase
• 由来する生物種: Aquifex aeolicus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37360.97

構造登録者

Emptage, R.P.,Daughtry, K.D.,Pemble IV, C.W.,Raetz, C.R.H. (登録日: 2012-04-04, 公開日: 2012-08-29, 最終更新日: 2023-09-13)

• 主引用文献: Emptage, R.P.,Daughtry, K.D.,Pemble, C.W.,Raetz, C.R.; Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface.; Proc.Natl.Acad.Sci.USA, 109:12956-12961, 2012; PubMed: 22826246; DOI: 10.1073/pnas.1206072109

実験手法

X-RAY DIFFRACTION (2.199 Å)