4EFX
Highly biologically active insulin with additional disulfide bond
Summary for 4EFX
Entry DOI | 10.2210/pdb4efx/pdb |
Descriptor | Insulin, ZINC ION, ... (4 entities in total) |
Functional Keywords | hormone |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 4 |
Total formula weight | 11235.55 |
Authors | Norrman, M.,Vinther, T.N. (deposition date: 2012-03-30, release date: 2013-03-06, Last modification date: 2024-04-03) |
Primary citation | Vinther, T.N.,Norrman, M.,Ribel, U.,Huus, K.,Schlein, M.,Steensgaard, D.B.,Pedersen, T.A.,Pettersson, I.,Ludvigsen, S.,Kjeldsen, T.,Jensen, K.J.,Hubalek, F. Insulin analog with additional disulfide bond has increased stability and preserved activity. Protein Sci., 22:296-305, 2013 Cited by PubMed: 23281053DOI: 10.1002/pro.2211 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
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