4EF5
Crystal structure of STING CTD
Summary for 4EF5
Entry DOI | 10.2210/pdb4ef5/pdb |
Related | 4EF4 |
Descriptor | Transmembrane protein 173 (2 entities in total) |
Functional Keywords | sting/mita/eris/mpys/tmem173, innate immune system, type i interferon, dimerization, c-di-gmp, 5 helices and 5 strands in single domain, immune system |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Multi-pass membrane protein: Q86WV6 |
Total number of polymer chains | 1 |
Total formula weight | 29848.46 |
Authors | Ouyang, S.,Ru, H.,Shaw, N.,Jiang, Y.,Niu, F.,Zhu, Y.,Qiu, W.,Li, Y.,Liu, Z.-J. (deposition date: 2012-03-29, release date: 2012-05-16, Last modification date: 2024-03-20) |
Primary citation | Ouyang, S.,Song, X.,Wang, Y.,Ru, H.,Shaw, N.,Jiang, Y.,Niu, F.,Zhu, Y.,Qiu, W.,Parvatiyar, K.,Li, Y.,Zhang, R.,Cheng, G.,Liu, Z.J. Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding Immunity, 36:1073-1086, 2012 Cited by PubMed: 22579474DOI: 10.1016/j.immuni.2012.03.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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