4EC4
XIAP-BIR3 in complex with a potent divalent Smac mimetic
Summary for 4EC4
Entry DOI | 10.2210/pdb4ec4/pdb |
Related | 4EB9 |
Descriptor | Baculoviral IAP repeat-containing protein 4, ZINC ION, (3S,6S,7S,9aS,3'S,6'S,7'S,9a'S)-N,N'-(benzene-1,4-diylbis{butane-4,1-diyl-1H-1,2,3-triazole-1,4-diyl[(S)-phenylmethanediyl]})bis[7-(hydroxymethyl)-6-{[(2S)-2-(methylamino)butanoyl]amino}-5-oxooctahydro-1H-pyrrolo[1,2-a]azepine-3-carboxamide], ... (6 entities in total) |
Functional Keywords | zinc finger, apoptosis inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P98170 |
Total number of polymer chains | 10 |
Total formula weight | 149595.95 |
Authors | Mastrangelo, E.,Cossu, F.,Bolognesi, M.,Milani, M. (deposition date: 2012-03-26, release date: 2012-12-05, Last modification date: 2023-09-13) |
Primary citation | Cossu, F.,Milani, M.,Vachette, P.,Malvezzi, F.,Grassi, S.,Lecis, D.,Delia, D.,Drago, C.,Seneci, P.,Bolognesi, M.,Mastrangelo, E. Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic. Plos One, 7:e49527-e49527, 2012 Cited by PubMed: 23166698DOI: 10.1371/journal.pone.0049527 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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