4EC3

Structure of berberine bridge enzyme, H174A variant in complex with (S)-reticuline

4EC3 の概要

• エントリーDOI: 10.2210/pdb4ec3/pdb
• 関連するPDBエントリー: 3D2D 3D2J 3FW7 3FW8
• 分子名称: Reticuline oxidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... (7 entities in total)
• 機能のキーワード: p-cresol methyl hydroxylase superfamily, oxidoreductase, fad, bi-covalent flavinylation
• 由来する生物種: Eschscholzia californica (California poppy)
• 細胞内の位置: Cytoplasmic vesicle: P30986
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 60252.82

構造登録者

Winkler, A.,Macheroux, P.,Gruber, K. (登録日: 2012-03-26, 公開日: 2012-07-18, 最終更新日: 2023-09-13)

• 主引用文献: Wallner, S.,Winkler, A.,Riedl, S.,Dully, C.,Horvath, S.,Gruber, K.,Macheroux, P.; Catalytic and structural role of a conserved active site histidine in berberine bridge enzyme.; Biochemistry, 51:6139-6147, 2012; PubMed: 22757961; DOI: 10.1021/bi300411n

実験手法

X-RAY DIFFRACTION (2.6501 Å)