4EC2

Crystal structure of trimeric frataxin from the yeast Saccharomyces cerevisiae, complexed with ferrous

4EC2 の概要

• エントリーDOI: 10.2210/pdb4ec2/pdb
• 関連するPDBエントリー: 2FQL 3OEQ 3OER
• 分子名称: Frataxin homolog, mitochondrial, FE (II) ION (2 entities in total)
• 機能のキーワード: alpha/beta sandwich, metallochaperone, iron-storage, transport protein
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast)
• 細胞内の位置: Mitochondrion matrix : Q07540
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13727.03

構造登録者

Soderberg, C.A.G.,Rajan, S.,Gakh, O.,Isaya, G.,Al-Karadaghi, S. (登録日: 2012-03-26, 公開日: 2013-01-30, 最終更新日: 2023-09-13)

• 主引用文献: Soderberg, C.A.,Rajan, S.,Shkumatov, A.V.,Gakh, O.,Schaefer, S.,Ahlgren, E.C.,Svergun, D.I.,Isaya, G.,Al-Karadaghi, S.; The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization.; J.Biol.Chem., 288:8156-8167, 2013; PubMed: 23344952; DOI: 10.1074/jbc.M112.442285

実験手法

X-RAY DIFFRACTION (3.002 Å)