4EBK

Crystal structure of aminoglycoside 4'-O-adenylyltransferase ANT(4')-IIb, tobramycin-bound

Summary for 4EBK

• Entry DOI: 10.2210/pdb4ebk/pdb
• Related: 4EBJ
• Descriptor: Aminoglycoside nucleotidyltransferase, TOBRAMYCIN, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, niaid, national institute of allergy and infectious diseases, alpha/beta protein, nucleotidyltransferase (nt) domain, antibiotic resistance, aminoglycoside 4'-o-adenylyltransferase, transferase, aminoglycoside antibiotics, tobramycin, amikacin, intracellular
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 64833.88

Authors

Stogios, P.J.,Dong, A.,Minasov, G.,Evdokimova, E.,Egorova, O.,Yim, V.,Kudritska, M.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-03-23, release date: 2012-04-04, Last modification date: 2024-11-06)

• Primary citation: Stogios, P.J.,Dong, A.,Minasov, G.,Evdokimova, E.,Egorova, O.,Yim, V.,Kudritska, M.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal structure of aminoglycoside 4'-O-adenylyltransferase ANT(4')-IIb, tobramycin-bound; To be Published,

Experimental method

X-RAY DIFFRACTION (2.15 Å)