4EAQ

Crystal structure of Thymidylate Kinase from Staphylococcus aureus in complex with 3'-Azido-3'-Deoxythymidine-5'-Monophosphate

Summary for 4EAQ

• Entry DOI: 10.2210/pdb4eaq/pdb
• Related: 4DWJ
• Descriptor: Thymidylate kinase, 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE (3 entities in total)
• Functional Keywords: structural genomics, psi-biology, midwest center for structural genomics, mcsg, mtbi, thymidylate kinase, transferase, transferase-transferase inhibitor complex, structures of mtb proteins conferring susceptibility to known mtb inhibitors, transferase/transferase inhibitor
• Biological source: Staphylococcus aureus subsp. aureus
• Total number of polymer chains: 2
• Total formula weight: 53091.48

Authors

Filippova, E.V.,Minasov, G.,Shuvalova, L.,Kiryukhina, O.,Jedrzejczak, R.,Babnigg, G.,Rubin, E.,Sacchettini, J.,Joachimiak, A.,Anderson, W.F.,Midwest Center for Structural Genomics (MCSG),Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) (deposition date: 2012-03-22, release date: 2012-04-11, Last modification date: 2023-09-13)

• Primary citation: Filippova, E.V.,Minasov, G.,Shuvalova, L.,Kiryukhina, O.,Jedrzejczak, R.,Joachimiak, A.,Anderson, W.F.; Crystal structure of Thymidylate Kinase from Staphylococcus aureus in complex with 3'-Azido-3'-Deoxythymidine-5'-Monophosphate; To be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)