4E9Z
Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with quinuclidine BPH-651 in the S1 site
Summary for 4E9Z
Entry DOI | 10.2210/pdb4e9z/pdb |
Related | 4E9U 4EA0 4EA1 4EA2 |
Descriptor | Dehydrosqualene synthase, (3R)-3-biphenyl-4-yl-1-azabicyclo[2.2.2]octan-3-ol (3 entities in total) |
Functional Keywords | bph-651, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 1 |
Total formula weight | 34640.40 |
Authors | Lin, F.-Y.,Liu, Y.-L.,Oldfield, E. (deposition date: 2012-03-21, release date: 2012-04-25, Last modification date: 2023-09-13) |
Primary citation | Lin, F.Y.,Liu, Y.L.,Li, K.,Cao, R.,Zhu, W.,Axelson, J.,Pang, R.,Oldfield, E. Head-to-Head Prenyl Tranferases: Anti-Infective Drug Targets. J.Med.Chem., 55:4367-4372, 2012 Cited by PubMed: 22486710DOI: 10.1021/jm300208p PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.06 Å) |
Structure validation
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