4E7H

PFV intasome prior to 3'-processing, Apo form (UI-Apo)

4E7H の概要

• エントリーDOI: 10.2210/pdb4e7h/pdb
• 関連するPDBエントリー: 3DLR 3OY9 3OYA
• 分子名称: Pro-Pol polyprotein, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*AP*AP*T)-3'), ... (8 entities in total)
• 機能のキーワード: protein-dna complex, tetramer, hhcc motif, endonuclease, metal-binding, multifunctional enzyme, nuclease, nucleotidyltransferase, nucleus, transferase, virion, dna-binding, zinc-binding, viral protein, recombination, viral protein-dna complex, recombination-dna complex, recombination/dna
• 由来する生物種: Human spumaretrovirus (SFVcpz(hu)); 詳細
• 細胞内の位置: Integrase: Virion (Potential). Protease/Reverse transcriptase/ribonuclease H: Host nucleus (By similarity): P14350
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 102053.73

構造登録者

Hare, S.,Cherepanov, P. (登録日: 2012-03-17, 公開日: 2012-05-23, 最終更新日: 2023-09-13)

• 主引用文献: Hare, S.,Maertens, G.N.,Cherepanov, P.; 3'-Processing and strand transfer catalysed by retroviral integrase in crystallo.; Embo J., 31:3020-3028, 2012; PubMed: 22580823; DOI: 10.1038/emboj.2012.118

実験手法

X-RAY DIFFRACTION (2.5701 Å)