4E5L
Crystal structure of avian influenza virus PAn bound to compound 6
Summary for 4E5L
Entry DOI | 10.2210/pdb4e5l/pdb |
Related | 4E5E 4E5F 4E5G 4E5H 4E5I 4E5J |
Descriptor | Polymerase protein PA, MANGANESE (II) ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | endonuclease domain, h5n1 subtype, viral protein, transcription |
Biological source | Influenza A virus More |
Cellular location | Host cytoplasm . Host nucleus : Q5EP34 |
Total number of polymer chains | 4 |
Total formula weight | 89488.32 |
Authors | DuBois, R.M.,Slavish, P.J.,Webb, T.R.,White, S.W. (deposition date: 2012-03-14, release date: 2012-08-08, Last modification date: 2023-09-13) |
Primary citation | Dubois, R.M.,Slavish, P.J.,Baughman, B.M.,Yun, M.K.,Bao, J.,Webby, R.J.,Webb, T.R.,White, S.W. Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease. Plos Pathog., 8:e1002830-e1002830, 2012 Cited by PubMed: 22876176DOI: 10.1371/journal.ppat.1002830 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.469 Å) |
Structure validation
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