4E5L

Crystal structure of avian influenza virus PAn bound to compound 6

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Polymerase protein PA	polymer	187	21916.0	4	UniProt (Q5EP34)	Influenza A virus	polymerase acidic protein
2	E, F, J, K, O... (A, B, C, D)	MANGANESE (II) ION	non-polymer		54.9	8	Chemie (MN)
3	G, H, L, M, Q... (A, B, C, D)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
4	I, N, S, X (A, B, C, D)	2,3-DIHYDROXY-BENZOIC ACID	non-polymer		154.1	4	Chemie (DBH)
5	AA, BA, Y, Z (C, D, A, B)	water	water		18.0	55	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 50 (UniProt: Q5EP34)
A, B, C, D: 73 - 196 (UniProt: Q5EP34)

PDB	External Database	Details
Gly 50	-	linker
Gly 50	-	linker
Ser 50	-	linker
Ala 196	-	expression tag
Ala 196	-	expression tag
Ala 197	-	expression tag
Glu 198	-	expression tag
Leu 199	-	expression tag
Ala 200	-	expression tag
Leu 201	-	expression tag
Val 202	-	expression tag
Pro 203	-	expression tag
Arg 204	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	87663.8
Non-Polymers*	Number of molecules	20
	Total formula weight	1824.5
All*	Total formula weight	89488.3

*Water molecules are not included.