4E4W

Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer

Summary for 4E4W

• Entry DOI: 10.2210/pdb4e4w/pdb
• Related: 4FMN 4FMO
• Descriptor: DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, GLYCEROL, ... (6 entities in total)
• Functional Keywords: mismatch repair, mutl, endonuclease, zn-binding protein, dna damage, dna repair, hydrolase
• Biological source: Saccharomyces cerevisiae S288c (Baker's yeast); More
• Cellular location: Nucleus: P38920 P14242
• Total number of polymer chains: 2
• Total formula weight: 61648.41

Authors

Gueneau, E.,Legrand, P.,Charbonnier, J.B. (deposition date: 2012-03-13, release date: 2013-02-20, Last modification date: 2024-02-28)

• Primary citation: Gueneau, E.,Dherin, C.,Legrand, P.,Tellier-Lebegue, C.,Gilquin, B.,Bonnesoeur, P.,Londino, F.,Quemener, C.,Le Du, M.H.,Marquez, J.A.,Moutiez, M.,Gondry, M.,Boiteux, S.,Charbonnier, J.B.; Structure of the MutLalpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.; Nat.Struct.Mol.Biol., 20:461-468, 2013; PubMed: 23435383; DOI: 10.1038/nsmb.2511

Experimental method

X-RAY DIFFRACTION (2.5 Å)