4E2X

X-ray Structure of the Y222F mutant of TcaB9, a C-3'-Methyltransferase, in Complex with S-Adenosyl-L-Homocysteine and dTDP

Summary for 4E2X

• Entry DOI: 10.2210/pdb4e2x/pdb
• Related: 4E2W 4E2Y 4E2Z 4E30 4E31 4E32 4E33
• Descriptor: TcaB9, ZINC ION, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: kijanose, tetronitrose, tetradeoxy sugar, sugar methylation, transferase
• Biological source: Micromonospora chalcea
• Total number of polymer chains: 1
• Total formula weight: 47175.19

Authors

Bruender, N.A.,Holden, H.M. (deposition date: 2012-03-09, release date: 2012-04-25, Last modification date: 2023-09-13)

• Primary citation: Bruender, N.A.,Holden, H.M.; Probing the catalytic mechanism of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose.; Protein Sci., 21:876-886, 2012; PubMed: 22495991; DOI: 10.1002/pro.2074

Experimental method

X-RAY DIFFRACTION (1.4 Å)