4E17

Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin

Summary for 4E17

• Entry DOI: 10.2210/pdb4e17/pdb
• Related: 4E18
• Descriptor: Vinculin, Catenin alpha-1 (3 entities in total)
• Functional Keywords: four helix bundle, cell adhesion
• Biological source: Gallus gallus (chicken); More
• Cellular location: Cytoplasm, cytoskeleton: P12003 P26231
• Total number of polymer chains: 2
• Total formula weight: 33783.76

Authors

Choi, H.-J.,Pokutta, S.,Cadwell, G.W.,Bankston, L.A.,Liddington, R.C.,Weis, W.I. (deposition date: 2012-03-05, release date: 2012-05-16, Last modification date: 2023-09-13)

• Primary citation: Choi, H.-J.,Pokutta, S.,Bankston, L.,Liddington, R.,Weis, W.I.; Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin; To be Published,

Experimental method

X-RAY DIFFRACTION (2.304 Å)