4DXH
Horse liver alcohol dehydrogenase complexed with NAD+ and 2,2,2-trifluoroethanol
Summary for 4DXH
Entry DOI | 10.2210/pdb4dxh/pdb |
Related | 1HLD 1N92 1P1R 3OQ6 4DWV |
Descriptor | Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total) |
Functional Keywords | alcohol dehydrogenase, nad+, trifluoroethanol, michaelis complex rossmann fold, oxidoreductase |
Biological source | Equus caballus (domestic horse,equine) |
Cellular location | Cytoplasm: P00327 |
Total number of polymer chains | 2 |
Total formula weight | 81967.81 |
Authors | Plapp, B.V.,Ramaswamy, S. (deposition date: 2012-02-27, release date: 2012-04-11, Last modification date: 2023-09-20) |
Primary citation | Plapp, B.V.,Ramaswamy, S. Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD(+) and Fluoroalcohols Define Strained Michaelis Complexes. Biochemistry, 51:4035-4048, 2012 Cited by PubMed: 22531044DOI: 10.1021/bi300378n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.12 Å) |
Structure validation
Download full validation report