4DXD
Staphylococcal Aureus FtsZ in complex with 723
Summary for 4DXD
Entry DOI | 10.2210/pdb4dxd/pdb |
Descriptor | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, 3-[(6-chloro[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide, ... (4 entities in total) |
Functional Keywords | rossmann fold, gtpase, gtp binding, cell cycle-inhibitor complex, cell cycle/inhibitor |
Biological source | Staphylococcus aureus |
Cellular location | Cytoplasm (By similarity): P0A031 |
Total number of polymer chains | 1 |
Total formula weight | 42706.63 |
Authors | Lu, J.,Soisson, S.M. (deposition date: 2012-02-27, release date: 2012-05-23, Last modification date: 2024-02-28) |
Primary citation | Tan, C.M.,Therien, A.G.,Lu, J.,Lee, S.H.,Caron, A.,Gill, C.J.,Lebeau-Jacob, C.,Benton-Perdomo, L.,Monteiro, J.M.,Pereira, P.M.,Elsen, N.L.,Wu, J.,Deschamps, K.,Petcu, M.,Wong, S.,Daigneault, E.,Kramer, S.,Liang, L.,Maxwell, E.,Claveau, D.,Vaillancourt, J.,Skorey, K.,Tam, J.,Wang, H.,Meredith, T.C.,Sillaots, S.,Wang-Jarantow, L.,Ramtohul, Y.,Langlois, E.,Landry, F.,Reid, J.C.,Parthasarathy, G.,Sharma, S.,Baryshnikova, A.,Lumb, K.J.,Pinho, M.G.,Soisson, S.M.,Roemer, T. Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics. Sci Transl Med, 4:126ra35-126ra35, 2012 Cited by PubMed: 22440737DOI: 10.1126/scitranslmed.3003592 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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