4DXD

Staphylococcal Aureus FtsZ in complex with 723

4DXD の概要

• エントリーDOI: 10.2210/pdb4dxd/pdb
• 分子名称: Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, 3-[(6-chloro[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide, ... (4 entities in total)
• 機能のキーワード: rossmann fold, gtpase, gtp binding, cell cycle-inhibitor complex, cell cycle/inhibitor
• 由来する生物種: Staphylococcus aureus
• 細胞内の位置: Cytoplasm (By similarity): P0A031
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42706.63

構造登録者

Lu, J.,Soisson, S.M. (登録日: 2012-02-27, 公開日: 2012-05-23, 最終更新日: 2024-02-28)

• 主引用文献: Tan, C.M.,Therien, A.G.,Lu, J.,Lee, S.H.,Caron, A.,Gill, C.J.,Lebeau-Jacob, C.,Benton-Perdomo, L.,Monteiro, J.M.,Pereira, P.M.,Elsen, N.L.,Wu, J.,Deschamps, K.,Petcu, M.,Wong, S.,Daigneault, E.,Kramer, S.,Liang, L.,Maxwell, E.,Claveau, D.,Vaillancourt, J.,Skorey, K.,Tam, J.,Wang, H.,Meredith, T.C.,Sillaots, S.,Wang-Jarantow, L.,Ramtohul, Y.,Langlois, E.,Landry, F.,Reid, J.C.,Parthasarathy, G.,Sharma, S.,Baryshnikova, A.,Lumb, K.J.,Pinho, M.G.,Soisson, S.M.,Roemer, T.; Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics.; Sci Transl Med, 4:126ra35-126ra35, 2012; PubMed: 22440737; DOI: 10.1126/scitranslmed.3003592

実験手法

X-RAY DIFFRACTION (2.01 Å)