4DXA

Co-crystal structure of Rap1 in complex with KRIT1

Summary for 4DXA

• Entry DOI: 10.2210/pdb4dxa/pdb
• Descriptor: Ras-related protein Rap-1b, Krev interaction trapped protein 1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... (5 entities in total)
• Functional Keywords: gtpase, ferm, protein-protein interaction, gtp binding, cytoplasmic, protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane: P61224; Membrane; Peripheral membrane protein (Probable): O00522
• Total number of polymer chains: 2
• Total formula weight: 57142.55

Authors

Li, X.,Zhang, R.,Boggon, T.J. (deposition date: 2012-02-27, release date: 2012-05-16, Last modification date: 2023-09-13)

• Primary citation: Li, X.,Zhang, R.,Draheim, K.M.,Liu, W.,Calderwood, D.A.,Boggon, T.J.; Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1).; J.Biol.Chem., 287:22317-22327, 2012; PubMed: 22577140; DOI: 10.1074/jbc.M112.361295

Experimental method

X-RAY DIFFRACTION (1.95 Å)