4DXA

Co-crystal structure of Rap1 in complex with KRIT1

4DXA の概要

• エントリーDOI: 10.2210/pdb4dxa/pdb
• 分子名称: Ras-related protein Rap-1b, Krev interaction trapped protein 1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... (5 entities in total)
• 機能のキーワード: gtpase, ferm, protein-protein interaction, gtp binding, cytoplasmic, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane: P61224; Membrane; Peripheral membrane protein (Probable): O00522
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 57142.55

構造登録者

Li, X.,Zhang, R.,Boggon, T.J. (登録日: 2012-02-27, 公開日: 2012-05-16, 最終更新日: 2023-09-13)

• 主引用文献: Li, X.,Zhang, R.,Draheim, K.M.,Liu, W.,Calderwood, D.A.,Boggon, T.J.; Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1).; J.Biol.Chem., 287:22317-22327, 2012; PubMed: 22577140; DOI: 10.1074/jbc.M112.361295

実験手法

X-RAY DIFFRACTION (1.95 Å)