4DWY

Interactions of Mn2+ with a non-self-complementary Z-type DNA duplex

4DWY の概要

• エントリーDOI: 10.2210/pdb4dwy/pdb
• 関連するPDBエントリー: 3FQ5 3G2A 3ULM 3ULN 3ULO 3UM4 4DY8
• 分子名称: DNA (5'-D(*CP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*G)-3'), MANGANESE (II) ION, ... (4 entities in total)
• 機能のキーワード: z-type dna double helices, dna
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 7348.72

構造登録者

Mandal, P.K.,Venkadesh, S.,Gautham, N. (登録日: 2012-02-27, 公開日: 2012-11-28, 最終更新日: 2024-03-20)

主引用文献

Mandal, P.K.,Venkadesh, S.,Gautham, N.
Interactions of Mn(2+) with a non-self-complementary Z-type DNA duplex
Acta Crystallogr.,Sect.F, 68:1420-1426, 2012

PubMed Abstract: Crystal structures of the hexanucleotide d(CACGCG)·d(CGCGTG) were determined in two crystal lattices when different concentrations of the counterion Mn2+ were used in crystallization. The availability of Mn2+ during the crystallization process appears to play an important role in inducing different crystal packings that lead to crystals belonging to the two space groups P2(1) and P6(5). Analysis of the molecular interactions of Mn2+ with the Z-form duplexes shows direct coordination to the purine residues G and A.

PubMed: 23192018
DOI: 10.1107/S1744309112041759

実験手法

X-RAY DIFFRACTION (1.61 Å)