4DWA

Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpUpC trinucleotide

4DWA の概要

• エントリーDOI: 10.2210/pdb4dwa/pdb
• 関連するPDBエントリー: 4DVK 4DVL 4DVN 4DW3 4DW5 4DW7
• 分子名称: E(rns) glycoprotein, RNA (5'-R(*CP*UP*C)-3'), beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: virus glycoprotein, t2 ribonuclease, viral protein-rna complex, viral protein/rna
• 由来する生物種: Bovine viral diarrhea virus (BVDV)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 43582.82

構造登録者

Krey, T.,Bontems, F.,Vonrhein, C.,Vaney, M.-C.,Bricogne, G.,Ruemenapf, T.,Rey, F.A. (登録日: 2012-02-24, 公開日: 2012-05-23, 最終更新日: 2023-09-13)

• 主引用文献: Krey, T.,Bontems, F.,Vonrhein, C.,Vaney, M.C.,Bricogne, G.,Rumenapf, T.,Rey, F.A.; Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.; Structure, 20:862-873, 2012; PubMed: 22579253; DOI: 10.1016/j.str.2012.03.018

実験手法

X-RAY DIFFRACTION (3.01 Å)