4DW7

Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpU dinucleotide

Summary for 4DW7

• Entry DOI: 10.2210/pdb4dw7/pdb
• Related: 4DVK 4DVL 4DVN 4DW3 4DW4 4DW5
• Descriptor: E(rns) glycoprotein, 5'-R(*CP*U)-3', beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: virus glycoprotein, t2 ribonuclease, viral protein, viral protein-rna complex, viral protein/rna
• Biological source: Bovine viral diarrhea virus 1-CP7; More
• Total number of polymer chains: 4
• Total formula weight: 43467.69

Authors

Krey, T.,Bontems, F.,Vonrhein, C.,Vaney, M.-C.,Bricogne, G.,Ruemenapf, T.,Rey, F.A. (deposition date: 2012-02-24, release date: 2012-05-23, Last modification date: 2024-06-05)

• Primary citation: Krey, T.,Bontems, F.,Vonrhein, C.,Vaney, M.C.,Bricogne, G.,Rumenapf, T.,Rey, F.A.; Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.; Structure, 20:862-873, 2012; PubMed: 22579253; DOI: 10.1016/j.str.2012.03.018

Experimental method

X-RAY DIFFRACTION (3.08 Å)