4DUN

1.76A X-ray Crystal Structure of a Putative Phenazine Biosynthesis PhzC/PhzF Protein from Clostridium difficile (strain 630)

Summary for 4DUN

• Entry DOI: 10.2210/pdb4dun/pdb
• Descriptor: Putative phenazine biosynthesis PhzC/PhzF protein, SULFATE ION, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, biosynthetic protein
• Biological source: Clostridium difficile
• Total number of polymer chains: 1
• Total formula weight: 30083.09

Authors

Brunzelle, J.S.,Wawrzak, W.,Kudritska, M.,Anderson, W.F.,Savchenko, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-02-22, release date: 2012-03-14, Last modification date: 2026-04-29)

Primary citation

Rosas-Lemus, M.,Dey, S.,Minasov, G.,Tan, K.,Anderson, S.M.,Brunzelle, J.,Nocadello, S.,Shabalin, I.,Filippova, E.,Halavaty, A.,Kim, Y.,Maltseva, N.,Osipiuk, J.,Minor, W.,Joachimiak, A.,Savchenko, A.,Anderson, W.F.,Satchell, K.J.F.
A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile.
Microbiol Resour Announc, 12:e0050723-e0050723, 2023

PubMed Abstract: causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen.

PubMed: 37747257
DOI: 10.1128/MRA.00507-23

Experimental method

X-RAY DIFFRACTION (1.76 Å)