4DU2

cytochrome P450 BM3h-B7 MRI sensor bound to dopamine

Summary for 4DU2

Entry DOI	10.2210/pdb4du2/pdb
Related	4DTW 4DTY 4DTZ 4DUA 4DUB 4DUC 4DUD 4DUE 4DUF
Descriptor	cytochrome P450 BM3 variant B7, PROTOPORPHYRIN IX CONTAINING FE, L-DOPAMINE, ... (4 entities in total)
Functional Keywords	cytochrome p450, mri contrast sensor, directed evolution, oxidoreductase
Biological source	Bacillus megaterium
Cellular location	Cytoplasm : P14779
Total number of polymer chains	2
Total formula weight	108987.54
Authors	Brustad, E.M.,Lelyveld, V.S.,Snow, C.D.,Crook, N.,Martinez, F.M.,Scholl, T.J.,Jasanoff, A.,Arnold, F.H. (deposition date: 2012-02-21, release date: 2012-06-13, Last modification date: 2023-09-13)
Primary citation	Brustad, E.M.,Lelyveld, V.S.,Snow, C.D.,Crook, N.,Jung, S.T.,Martinez, F.M.,Scholl, T.J.,Jasanoff, A.,Arnold, F.H. Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. J.Mol.Biol., 422:245-262, 2012 Cited by PubMed: 22659321 DOI: 10.1016/j.jmb.2012.05.029 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation