4DO8

Crystal structure of the muscarinic toxin MT1

4DO8 の概要

• エントリーDOI: 10.2210/pdb4do8/pdb
• 関連するPDBエントリー: 1FF4 2VLW 3FEV 3NEQ
• 分子名称: Muscarinic toxin 1, THIOCYANATE ION, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: snake toxin, three-finger toxin fold, muscarinic toxin, muscarinic m1 receptor, neurones, muscarinic m4 receptor, adrenergic receptor, toxin
• 由来する生物種: Dendroaspis angusticeps (Eastern green mamba)
• 細胞内の位置: Secreted: P81030
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 15168.37

構造登録者

Fruchart-Gaillard, C.,Mournier, G.,Vera, L.,Servent, D.,Stura, E.A. (登録日: 2012-02-09, 公開日: 2012-06-27, 最終更新日: 2024-04-03)

• 主引用文献: Fruchart-Gaillard, C.,Mourier, G.,Blanchet, G.,Vera, L.,Gilles, N.,Menez, R.,Marcon, E.,Stura, E.A.,Servent, D.; Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.; Plos One, 7:e39166-e39166, 2012; PubMed: 22720062; DOI: 10.1371/journal.pone.0039166

実験手法

X-RAY DIFFRACTION (1.802 Å)