4DLQ

Crystal structure of the GAIN and HormR domains of CIRL 1/Latrophilin 1 (CL1)

Summary for 4DLQ

• Entry DOI: 10.2210/pdb4dlq/pdb
• Related: 4DLO
• Descriptor: Latrophilin-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: gain domain, includes the gps motif, hormone binding domain, autoproteolysis, a-latrotoxin, extracellular domain, signaling protein
• Biological source: Rattus norvegicus (rat); More
• Total number of polymer chains: 2
• Total formula weight: 46466.97

Authors

Arac, D.,Boucard, A.A.,Bolliger, M.F.,Nguyen, J.,Soltis, M.,Sudhof, T.C.,Brunger, A.T. (deposition date: 2012-02-06, release date: 2012-02-22, Last modification date: 2020-07-29)

• Primary citation: Arac, D.,Boucard, A.A.,Bolliger, M.F.,Nguyen, J.,Soltis, S.M.,Sudhof, T.C.,Brunger, A.T.; A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.; Embo J., 31:1364-1378, 2012; PubMed: 22333914; DOI: 10.1038/emboj.2012.26

Experimental method

X-RAY DIFFRACTION (1.85 Å)