4DKK
The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer
Summary for 4DKK
| Entry DOI | 10.2210/pdb4dkk/pdb |
| Descriptor | Double-stranded RNA-binding protein Staufen homolog 1, CITRATE ANION, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | rbd, beta sheet, swapping-motif, dimerization, protein binding, rna binding protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: O95793 |
| Total number of polymer chains | 1 |
| Total formula weight | 12700.69 |
| Authors | Gleghorn, M.L. (deposition date: 2012-02-03, release date: 2013-03-20, Last modification date: 2024-03-13) |
| Primary citation | Gleghorn, M.L.,Gong, C.,Kielkopf, C.L.,Maquat, L.E. Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay. Nat.Struct.Mol.Biol., 20:515-524, 2013 Cited by PubMed: 23524536DOI: 10.1038/nsmb.2528 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.701 Å) |
Structure validation
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