4DKJ

CpG specific methyltransferase in complex with target DNA

4DKJ の概要

• エントリーDOI: 10.2210/pdb4dkj/pdb
• 関連するPDBエントリー: 1MHT 2C7P 3PT6 3PT9 3PTA 4DA4
• 分子名称: Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(C37)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ... (6 entities in total)
• 機能のキーワード: cg-specificity, dna intercalation, cpg sequence, cytosine c5-methylation, c5-methylcytosine, nucleotide flipping, s-adenosyl-l-methionine-dependent methyltransferases, c-5 cytosine-specific dna methylases, dna (cytosine-5-)-methyltransferase activity, dna binding, dna (cytosine-5-)-methylation, intracellular, transferase-dna complex, transferase/dna
• 由来する生物種: Mycoplasma penetrans
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 56380.19

構造登録者

Wojciechowski, M.,Czapinska, H.,Bochtler, M. (登録日: 2012-02-03, 公開日: 2012-12-05, 最終更新日: 2023-09-13)

• 主引用文献: Wojciechowski, M.,Czapinska, H.,Bochtler, M.; CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI.; Proc.Natl.Acad.Sci.USA, 110:105-110, 2013; PubMed: 23248272; DOI: 10.1073/pnas.1207986110

実験手法

X-RAY DIFFRACTION (2.15 Å)