4DBB

The PTB domain of Mint1 is autoinhibited by a helix in the C-terminal linker region

4DBB の概要

• エントリーDOI: 10.2210/pdb4dbb/pdb
• 分子名称: Amyloid beta A4 precursor protein-binding family A member 1, CHLORIDE ION, ACETIC ACID, ... (6 entities in total)
• 機能のキーワード: x11s/mints, ptb domain, chimera protein, protein transport
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• 細胞内の位置: Cytoplasm . Isoform 2: Golgi apparatus : O35430
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18868.80

構造登録者

Tomchick, D.R.,Rizo, J.,Ho, A.,Xu, Y. (登録日: 2012-01-13, 公開日: 2012-03-07, 最終更新日: 2024-02-28)

• 主引用文献: Matos, M.F.,Xu, Y.,Dulubova, I.,Otwinowski, Z.,Richardson, J.M.,Tomchick, D.R.,Rizo, J.,Ho, A.; Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing.; Proc.Natl.Acad.Sci.USA, 109:3802-3807, 2012; PubMed: 22355143; DOI: 10.1073/pnas.1119075109

実験手法

X-RAY DIFFRACTION (1.901 Å)