4DAN

Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2-fluoroadenosine

Summary for 4DAN

Entry DOI	10.2210/pdb4dan/pdb
Related	4D8V 4D8X 4D8Y 4D98 4D9H 4DA0 4DA6 4DA7 4DA8 4DAB 4DAE 4DAO 4DAR
Descriptor	Purine nucleoside phosphorylase deoD-type, 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL (2 entities in total)
Functional Keywords	phosphorylase/hydrolase-like, transferase
Biological source	Bacillus subtilis
Total number of polymer chains	2
Total formula weight	55694.74
Authors	Giuseppe, P.O.,Martins, N.H.,Meza, A.N.,Murakami, M.T. (deposition date: 2012-01-13, release date: 2012-09-26, Last modification date: 2024-02-28)
Primary citation	de Giuseppe, P.O.,Martins, N.H.,Meza, A.N.,Dos Santos, C.R.,Pereira, H.D.,Murakami, M.T. Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7:e44282-e44282, 2012 Cited by PubMed: 22957058 DOI: 10.1371/journal.pone.0044282 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.56 Å)

Structure validation